Brandenburg Concerto no. 5
jathis:

isn’t this fucking Makani art? it looks like makani art

Reblogging for that fantastic look on that girls face. Oh you just know she is up to no good!

jathis:

isn’t this fucking Makani art? it looks like makani art

Reblogging for that fantastic look on that girls face. Oh you just know she is up to no good!

267198ed:

Curses, no, I shall continue until I cannot much longer, besides it is tomorrow so leave me be.

Haha, too clever. I love this movie.

sciencenote:

RNA studies under fire
High-throughput RNA sequencing has yielded some unexpected results in the past few years — including some that seem to rewrite conventional wisdom in genetics. But a few of those findings are now being challenged, as computational biologists warn of the statistical pitfalls that can lurk in data-intensive studies.
….
For their study, Dulac and Gregg used high-throughput RNA sequencing to search mouse RNA for single nucleotide polymorphisms (SNPs) — one-letter variations in genetic sequence. The researchers then asked whether the SNPs they found for each gene could be traced to one or to both parents. If the SNPs were encoded mainly by one parent’s copy of the gene, the team concluded that the gene was imprinted (see ‘The silence of the genes’).
…The debate has implications for any sequencing-based study that requires statisticians to identify rare genetic phenomena using relatively new methods. “If you don’t deal with the analytical details very carefully, you’re going to get into trouble because of the low signal-to-noise ratio” in these types of experiments, says Jin Billy Li, a genomicist at Stanford University who was one of the critics of Cheung’s RNA-editing paper.



I think it was certainly known for a while that these techniques had their downfalls.

sciencenote:

RNA studies under fire

High-throughput RNA sequencing has yielded some unexpected results in the past few years — including some that seem to rewrite conventional wisdom in genetics. But a few of those findings are now being challenged, as computational biologists warn of the statistical pitfalls that can lurk in data-intensive studies.

….

For their study, Dulac and Gregg used high-throughput RNA sequencing to search mouse RNA for single nucleotide polymorphisms (SNPs) — one-letter variations in genetic sequence. The researchers then asked whether the SNPs they found for each gene could be traced to one or to both parents. If the SNPs were encoded mainly by one parent’s copy of the gene, the team concluded that the gene was imprinted (see ‘The silence of the genes’).

…The debate has implications for any sequencing-based study that requires statisticians to identify rare genetic phenomena using relatively new methods. “If you don’t deal with the analytical details very carefully, you’re going to get into trouble because of the low signal-to-noise ratio” in these types of experiments, says Jin Billy Li, a genomicist at Stanford University who was one of the critics of Cheung’s RNA-editing paper.

I think it was certainly known for a while that these techniques had their downfalls.

Did I mention I love this comic book? Because I do. Today was lacking some serious John Constantine.

Did I mention I love this comic book? Because I do. Today was lacking some serious John Constantine.

humansofnewyork:

How a germaphobe gets to work.

Hey pal, Yuri Gagarin wants his suit back. :3

humansofnewyork:

How a germaphobe gets to work.

Hey pal, Yuri Gagarin wants his suit back. :3

ericanorth:

I am John Constantine, and I want to be anywhere but here.

ericanorth:

I am John Constantine, and I want to be anywhere but here.

speculumetaenigmate:


‘I’ll tell you the ultimate secret of magic. Any cunt could do it.’

John Constantine, Hellblazer.

speculumetaenigmate:

‘I’ll tell you the ultimate secret of magic. Any cunt could do it.’

John Constantine, Hellblazer.

shizui:

fighting haters by moonlight

winning fans by daylight

don’t need sailor scouts to help fight

he is the one named kanye west 

staceythinx:

DebraLee Wiseberg photographs aging metal with colorful results.

Oxidation can be beautiful :3

dollypirate:

I received a package from Finland. :)

Snorkmaiden stamps! <33

dollypirate:

I received a package from Finland. :)

Snorkmaiden stamps! <33

“May your pants be made from the finest silk of Paris and your shoes from England. May your gold be luminous and your watches Swiss.”

Spell your tumblr name with your tags. DO IT!

WHAT IS THIS INSANITY?!

Antony smells of dog

So many angry challah breads

Thugs life

Especially that little minx Lemmings

Let me in this house baby

Americans are crazy

Nancy Reagen says to just say no to drugs

Dr. Mobius has achieved Antony levels of obsession

Lady Gaga: Her swagger is Very Powerful

Or else I will beat you with my swag

Go to Olive Garden and ask for the kids menu

It looks like he is eyein some fine ass hoes

Caesar: bitch get outta mah grill I be eatin dis hotdog


Well, my blog is clearly full of quality.

it8bit:

Sci-FI NES Games from a Parallel Dimension

ianbrooksWe were unfortunate enough to live through such horrible movie-licensed games like Robocop, Total Recall, and E.T. (or as we usually refer to it: That Game Which Shall Not Be Named), but perhaps somewhere in an alternate timeline where good things happened and people knew how to make good movie-based vidya gaemz, we could have had such instant classics like “They Live!” (with real 3D glasses action? Give me that) and MST3K (do you play the movie they’re watching, or just Press A to quip?)

(vgjunk/io9)

wowfunniestposts:

eXPLODING FROM CUTENESS

Bored? click!